Fig. 4: Global epidemiology and intrainstitutional variation in disease- and health-associated species. | Nature Microbiology

Fig. 4: Global epidemiology and intrainstitutional variation in disease- and health-associated species.

From: Identification of gut microbial species linked with disease variability in a widely used mouse model of colitis

Fig. 4

a–c, Prevalence and abundance of disease- and health-associated species in SPF mice across international mouse facilities. a, Intrainstitute prevalence of D. muricolitica (purple), A. okayasuensis (red), A. faecis (green) and S. muris (blue). A species is defined as present in a sample if ≥0.01% shotgun metagenomic reads are assigned to it. Intrainstitute prevalence is calculated as the percentage of samples per institute in which a species is present. b, Bar plot indicating number of samples per institute. c, Heatmap of intrainstitute mean abundance for each species. In b and c, Institute names correspond with those in a. For mean abundance, data are the percentage of classified reads assigned to each species, with zero counts removed using Bayesian multiplicative replacement, followed by center log-ratio transformation.

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