Extended Data Fig. 4.: Influence of 3-HK administration on An. stephensi survival and P. berghei exflagellation. | Nature Microbiology

Extended Data Fig. 4.: Influence of 3-HK administration on An. stephensi survival and P. berghei exflagellation.

From: Anopheline mosquitoes are protected against parasite infection by tryptophan catabolism in gut microbiota

Extended Data Fig. 4.: Influence of 3-HK administration on An. stephensi survival and P. berghei exflagellation.

a, Fold change of 3-HK levels in control (n = 10) and 3-HK fed (n = 10) mosquitoes at 24 h (-24 h), 0 h (0 h) prior to and 24 h (24 h) post blood meal. Data are presented as mean ± s.e.m. b, Survival curve of control (n=46) and 3-HK fed (n=43) mosquitoes post an infectious blood meal. Results from one of two independent experiments are shown. c, Exflagellation rate monitored 15 min post infection in the control (-) and 3-HK fed (+) mosquitoes. Data were pooled from two independent experiments. Each dot represents an individual mosquito. Horizontal black bars indicate the median values (c). Significance was determined by two-sided Student’s t-test in (a), Log-rank (Mantel-Cox) test in (b) and Mann-Whitney test in (c).

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