Extended Data Fig. 6: Immunological differences between cohorts.
(a) PCA plot of gene expression across cohorts, based on PBMC RNA Seq data. Samples are partitioned into healthy controls (n = 13), rUTI patient baseline (enrollment; n = 12) and rUTI patient at time of UTI (n = 17). (b) Plasma eotaxin-1 levels in control women, and rUTI women at healthy enrollment and time of UTI. (c) Relative abundance of NK cells in control and rUTI women based on CIBERSORT output. Box plots display the median (center line), 25th and 75th percentiles (box), as well as data points within 1.5 IQR of the upper & lower quartiles (whiskers), and outliers beyond this range (dots).
