Extended Data Fig. 4: Within and between host mutational spectra for each of 96 tri nucleotide substitution classes.
From: Pneumococcal within-host diversity during colonization, transmission and treatment
Each spectra is displayed according to the 96 substitution classification defined by the substitution class (colour in the graph) and sequence context immediately 3′ and 5′ to the mutated base. The mutation types are given on the horizontal axes, while vertical axes depict the frequency of each type. Mutations observed using ancestral state reconstruction from genomes observed in different hosts are given above while mutations observed within a host are given in the bottom panels.
