Extended Data Fig. 5: Principal Component Analysis of the mutational spectra from different SARS-CoV-2 variants.
From: Divergent SARS-CoV-2 variant emerges in white-tailed deer with deer-to-human transmission
The first two principal components account for 65.5% of the variation among the samples. Variation in the spectra along the first principal component are associated with changes in the frequency of C > U mutations. Interestingly, samples along this component are also differentiated by host-type. Variation along the second principal component reflect changes in the frequency of G > U and G > A mutations. (A) The biplot showing a projection of all samples. (B) A simplified version of plot A highlighting the positions of white-tailed deer samples isolated from Ontario (Blue) and Quebec (Pink). A human isolate from Ontario appears in the same area of the plot (teal) as Ontario deer samples. Arrows are scaled to 30% of their original size to create a cleaner plot.
