Table 1 Calculations to determine the likelihood that an HIV+ CD4 T cell contributed to assay outcome
From: Monocyte-derived macrophages contain persistent latent HIV reservoirs
Participant | IUPM MDM | IUPM CD4 | No. CD3+ T cells in largest MDM-QVOA well | % CD3+/CD4+ cells in blood | No. CD4+ T cells in largest MDM-QVOA well | % chance of an HIV+ CD4 T cell in largest MDM-QVOA well |
|---|---|---|---|---|---|---|
CP11-1 | 0.44 | 1.59 | 0.4b | 53.9 | 0.2 | 0.00004 |
CP11-2 | 0.16 | 1.59a | 0.7b | 52.3 | 0.4 | 0.00006 |
CP11-3 | 0.41 | 1.59a | 13.1 | 54.6 | 7.1 | 0.00114 |
CP21-1 | 0.34 | 0.55 | 1.1 | 55.9 | 0.6 | 0.00004 |
CP21-2 | 0.28 | 0.55a | 0.5b | 56 | 0.3 | 0.00002 |
CP21-3 | 0.08 | 0.55a | 61.9 | 60 | 37.1 | 0.00206 |
CP25 | 0.24 | 8.08 | 0.8b | 42 | 0.4 | 0.00029 |
CP36-1 | 15.8 | 9.50 | 5.2 | 31.5 | 1.7 | 0.00157 |
CP36-2 | 0.6 | 2.40 | 1.7 | 42 | 0.7 | 0.00017 |
CP39 | <LOD | <LOD | 0.4b | 39.4 | 0.1 | NA |
CP56-1 | <LOD | 0.70 | 902.6 | 42.6 | 384.5 | 0.02691 |
CP56-2 | <LOD | 0.70a | 7.8 | 43.3 | 3.4 | 0.00024 |
CP67 | 2.84 | 1.12 | 0.1b | 38.4 | 0.0 | 0.00000 |
CP71 | <LOD | 0.52 | 3.3 | 40.2 | 1.3 | 0.00007 |
CP75 | <LOD | 1.78 | 0.2b | 74.4 | 0.1 | 0.00002 |
CP77 | <LOD | 13.84 | 10.6 | 61.2 | 6.5 | 0.00902 |
