Extended Data Fig. 3: Levels of anti-BA.5 antibody in mice passively transferred vaccine-elicited serum antibody.

(a) Levels of antiBA.5 spike IgG in serum of mice that were passively transferred naïve or immune sera. Amounts are compared to those in vaccine-elicited immune serum before transfer (n = 5 mice per group, columns indicate mean values). (b) Neutralizing antibody response against SARS-CoV-2 BA.5 using sera from naïve (circles) or spike protein vaccinated (grey squares) mice. Also shown is serum neutralizing antibody activity from recipient wild-type mice one day after transfer of immune sera (black squares). Data are representative of results with n = 5 mice per group.