Extended Data Fig. 6: Structure and sequence analyses of the NTP binding pocket in PurZ0, PurZ and PurA.
From: Alternative Z-genome biosynthesis pathway shows evolutionary progression from Archaea to phage

a, The NTP binding site of the EcPurA (PDB: 1CIB). b, Sequence logos of residues interacting with the purine moiety of NTPs in all PurA of bacteria. c, The NTP binding site of the GpPurZ0 (PDB: 7VF6). d, Sequence logos of residues interacting with the purine moiety of NTPs in PurZ0 of phages. e, The NTP binding site of the VpPurZ (PDB: 6FKO). f, Sequence logos of residues interacting with the purine moiety of NTPs in PurZ of phages.