Extended Data Fig. 6: Phylogenetic analyses of Glp in Bacteria.

(a) Maximum likelihood phylogeny of MoeA-like paralogs in Bacteria. The genomic context of Glp/MoeA paralogs is indicated for each branch, if conserved in at least two other cases. Non-conserved genes in the genomic context are indicated with gray rectangles without labels. Branches that correspond to C. glutamicum and M. tuberculosis species are indicated in red. Dots indicate UFB > 0.85. The scale bar represents the average number of substitutions per site. (b) Phyletic pattern for the presence of MoeA-like paralogs in Bacteria. Full circles indicate presence of the gene in more than 50% of the analyzed genomes of the phylum, darker pink indicates the presence of more than one copy. The phyletic pattern is represented on a reference Bacteria tree⁷³. Phyla were collapsed into a single branch for clarity. For the detailed analysis see Supplementary Table 4.