Extended Data Fig. 9: Status of known histone marks in the heterochromatic regions of pfap2-p truncated parasites.
From: DNA-binding protein PfAP2-P regulates parasite pathogenesis during malaria parasite blood stages
a-b, ChIP-seq profiles of various histone marks (H3K4me3, H3K9ac and H3K9me3) in the chromosome 7 (a) and in the promoter and gene body of a var gene (b) as examples. For ChIP-seq chromatin was sampled at 16 and 40 h.p.i. corresponding to the two peaks of pfap2-p expression. We have also provided the binding profile of PfAP2-P at both 16 and 40 h.p.i. for comparison. D;DMSO treated mock control; R: Rapamycin treated pfap2-p truncated parasites. Each track is input subtracted ChIP tracks.
