Extended Data Fig. 9: Phenotypic characterisation of resistant mutants.

A) Representative images of spot assays on Sabouraud agar medium of MFIG001 and mutant isolates. B) Radial growth was measured after 48 hours on Sabouraud agar medium. Data are presented as the mean ± s.d. of three experiments. P values were determined by two-sided ANOVA with Tukey multiple comparison between means from a sample size of n = 3. C) Sporulation was measured after 3 days by inoculating MM cultures with equal spores. Spores were harvested through Miracloth and counted on a haemocytometer. Data are presented as the mean ± s.d. of three experiments. P values were determined by two-sided ANOVA from a sample size of n = 3.