Fig. 2: ΦKZ proteins are co-sedimented with the host gene expression machinery.
From: Phage proteins target and co-opt host ribosomes immediately upon infection
a, Sedimentation profiles of selected ΦKZ proteins in HMW fractions. b, t-distributed stochastic neighbour embedding (t-SNE) clustering of sedimentation profiles revealed proteins that form large macromolecular complexes. ΦKZ RNAP subunits clustered together with ΦKZ079/-122/-176 and -264. ΦKZ019/-020/-56/-157 and -260.1 clustered with host RNAP proteins. ΦKZ216 and ΦKZ135 clustered with proteins of the 30S ribosomal subunit, and ΦKZ014/-105/-110/-206/-225/-234.1/-299 clustered with proteins of the 50S ribosomal subunit. Prot., protein; recomb.-med., recombination-mediator; put. struct., putative structural.
