Extended Data Table 2 Kinetic parameters (mean and standard deviation from replicates, n = 3) of Mpro inhibition by RAY1216 and PF-07321332 as determined by ODE method in DynaFit

From: Preclinical evaluation of the SARS-CoV-2 Mpro inhibitor RAY1216 shows improved pharmacokinetics compared with nirmatrelvir

  1. a, Kinetic parameters of WT Mpro inhibition. b, Kinetic parameters of P132H Mpro inhibition. See Enzyme kinetics section of Supplementary Information for details of data analysis procedures.
  2. Source data
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