Extended Data Fig. 4: Ability of RISK6 to identify GC6 adolescent and adult progressors.
From: Age and sex influence antibody profiles associated with tuberculosis progression
ROC curves were developed over the full study duration for the subset of individuals in GC6 for whom the RISK6 score was available. A) ROC curve indicates performance of RISK6 among all GC6 individuals (n = 35 progressors and n = 135 non-progressors). B) ROC curve for performance of RISK6 among GC6 adolescents (age 8–20 years, n = 12 progressors and n = 49 non-progressors) and adults (age ≥21 years, n = 23 progressors and n = 86 non-progressors). ROC curves were generated 50 times using randomly selected 80% of samples with group stratification. The mean curve is indicated in blue, with grey shading indicating one standard deviation. Mean AUC with 95% confidence interval is indicated.
