Extended Data Fig. 2: Expression of GINs and GPRs is up-regulated after exposure to C. elegans.

a, Transcripts per kilobase million (TPM) values of the differentially expressed Pth11-like GPCRs, with arrows indicating the five highly upregulated Pth11-like GPCRs. (The values represent the average of three independent biological replicates.). b, TPM values of the differentially expressed GPR2 and GPR3. (The values represent the average of three independent biological replicates.). c, d, Protein sequence alignment of Gins (c) and Gprs (d). Three levels of shading and three different symbols are used to indicate degrees of sequence similarity: black background with asterisk (*) indicates identical amino acids, intermediate grey background with colon (:) indicates conserved amino acids, and light grey with single dots (.) indicates semi-conserved amino acids.