Extended Data Fig. 4: Sequence alignment of cGAS and E2 homologs. | Nature Microbiology

Extended Data Fig. 4: Sequence alignment of cGAS and E2 homologs.

From: Phage defence system CBASS is regulated by a prokaryotic E2 enzyme that imitates the ubiquitin pathway

Extended Data Fig. 4: Sequence alignment of cGAS and E2 homologs.

a, Sequence alignment of the C-terminal residues of cGAS and CD-NTase homologs from other E2-CBASSs. A conserved C-terminal glycine is marked by a red triangle. See also Supplementary Fig. 1. b, Sequence alignment of E2 and its orthologs shows two conserved cysteine residues (marked by red triangles). See also Supplementary Fig. 2.

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