Extended Data Fig. 4: Matched confounders between ASD (n = 301) and NT (n = 301) in the balanced sub-cohort constructed by one-by-one pairing algorithm, including age (a), BMI (b), sex (c), sequencing batch (d), GI parameters (e) and dietary factors (f). | Nature Microbiology

Extended Data Fig. 4: Matched confounders between ASD (n = 301) and NT (n = 301) in the balanced sub-cohort constructed by one-by-one pairing algorithm, including age (a), BMI (b), sex (c), sequencing batch (d), GI parameters (e) and dietary factors (f).

From: Multikingdom and functional gut microbiota markers for autism spectrum disorder

Extended Data Fig. 4: Matched confounders between ASD (n = 301) and NT (n = 301) in the balanced sub-cohort constructed by one-by-one pairing algorithm, including age (a), BMI (b), sex (c), sequencing batch (d), GI parameters (e) and dietary factors (f).

Continuous data were compared using two-sided Mann-Whitney U test (two-sided test) and shown via the median (centre line), 25th and 75th percentiles (box limits) and the 5th and 95th percentiles (whiskers). Categorical variables were presented as proportions and were compared using two-sided Chi-squire test or Fisher’s exact test (expected count<5). Dietary patterns were assessed by principal components analysis. BMI, body mass index; GI, gastrointestinal. ASD, autism spectrum disorder; NT, neurotypical.

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