Extended Data Fig. 5: Attachment of ticks silenced for genes associated with the D-BAIBA metabolism.
From: Bacterial reprogramming of tick metabolism impacts vector fitness and susceptibility to infection
I. scapularis nymphs were injected with siRNA or scrambled control for beta-ureidopropionase 1 (upb1) or alanine-glyoxylate aminotransferase 2 (agxt2) and allowed to feed on uninfected C57BL/6 mice for 3 days. The attachment of silenced ticks compared to scrambled controls was recorded for (a) upb1 (n = 69 and 83) or (b) agxt2 (n = 76 and 110). Data are representative of two independent experiments where n = an individual tick. Statistical significance was evaluated by the Fisher’s exact test. NS=not significant. Significant p values (<0.05) are displayed in the figure.
