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Viral infection

Viral entry as a low barrier to zoonosis

Nature Microbiology volume 10, pages 272–273 (2025)Cite this article

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The hurdle for infection of human cells by many animal and insect viruses remains poorly understood. A study using a large-scale functional screening approach suggests that the entry step may be a lower barrier to zoonosis than previously anticipated.

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Fig. 1: Evaluating the role of cell entry in host species restriction of viruses.

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Authors and Affiliations

  1. Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA

    Sathvik Palakurty & Michael S. Diamond

  2. Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA

    Sathvik Palakurty & Michael S. Diamond

  3. Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA

    Michael S. Diamond

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  1. Sathvik Palakurty
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  2. Michael S. Diamond
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Correspondence to Michael S. Diamond.

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The authors declare no competing interests.

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Palakurty, S., Diamond, M.S. Viral entry as a low barrier to zoonosis. Nat Microbiol 10, 272–273 (2025). https://doi.org/10.1038/s41564-024-01909-1

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