Fig. 3: Gut microbiota profiles of participants with different responses to BSE.
a, PCo analysis of Bray–Curtis dissimilarities of gut microbiota at the species level at baseline between participants who showed a pronounced response (defined as a reduction of fasting blood glucose of at least 0.3 mmol l−1; n = 13) and a less pronounced response (n = 22) to BSE treatment (P = 0.001). Standard error bars for the principal coordinates are denoted. b, PCo analysis of species‐level Bray–Curtis dissimilarities at baseline and post-treatment in participants with a pronounced (n = 13) and less pronounced (n = 22) response to BSE (no significant differences between baseline and post-treatment; standard error bars are denoted). c, Significantly altered taxa at baseline (at adjusted P < 0.05) between participants with a pronounced (blue) and less pronounced (yellow) response to BSE. The x axis denotes log(fold change) of the taxa.
