Dysbiosis is a harbinger of severe intestinal pathologies driving enhanced susceptibility to colonization by opportunistic pathogens. Type 3 innate lymphoid cell-derived IL-22 harnesses pathogen colonization resistance by regulating the galactosylation status of intestinal epithelial cells.
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Bernink, J.H. The sweet side of IL-22. Nat Microbiol 10, 610–612 (2025). https://doi.org/10.1038/s41564-025-01945-5
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DOI: https://doi.org/10.1038/s41564-025-01945-5
