Extended Data Fig. 1: Characterization of Sau–Thoeris defense.
From: Bacterial TIR-based immune systems sense phage capsids to initiate defense
a) Tenfold serial dilutions of Φ80α-vir on lawns of S. aureus RN4220 carrying either an incomplete (thsB1/B2) or full (thsA/B1/B2) Thoeris operon in the bacterial chromosome. (b) Growth of S. aureus RN4220 harboring plasmids carrying either an incomplete (thsB1/B2) or full (thsA/B1/B2) Thoeris operon, determined as the OD600 of the cultures after infection with Φ80α-vir at MOI 0, 0.1 or 10. Mean of +/- S.D. of three biological replicates is reported.
