Fig. 1: Architecture of the HSV-1 HP complex bound to PTV and AMNV.
From: Structural and mechanistic insights into herpesvirus helicase–primase and its therapeutic inhibitors
a, Overview of the HSV-1 HP complex with the AMNV composite map, created by combining separately refined maps of two bodies. The surface volume is colour-coded as indicated below. Scale bar, 10 Å. b, Ribbon diagram of the solved HSV-1 HP complex structure with AMNV. In the lower right image, AMNV is shown as a stick model with experimental density contoured at 1.0σ, while in the lower left image, PTV is presented as a stick model with experimental density also contoured at 1.0σ. The colour scheme is consistent across all figures unless otherwise noted. c, Chemical structures of PTV and AMNV.
