Extended Data Fig. 3: CD4+ and CD8+ T-cell responses specific to TET and SARS-CoV-2 JN.1.

a, Stimulation index fold increases of CD4 + /CD69+ /CD134+ populations in relation to DMSO. b, Stimulation index fold increases of CD8+ /CD69+ /CD134+populations in relation to DMSO. Blue dots indicate individuals with no previous avian influenza vaccinations, and red dots indicate individuals with previous avian influenza vaccinations. The graphs display geometric mean indices (lines) and 95% confidence intervals (whiskers). Dashed line indicates the cut-off threshold. Statistical significance was determined with Wilcoxon matched-pairs signed rank test. Two-sided p < 0.05 is considered a significant difference.