Extended Data Fig. 1: S protein conservation in Bacilli.
From: Pneumococcal S protein coordinates cell wall modification and repair to resist host antimicrobials
(A) Multiple sequence alignment of Streptococci S protein sequences. Sequence similarities are highlighted in dark blue. (B) Percentages indicate the percent identity for each species compared to S. pneumoniae S protein. L. monocytogenes S protein identity score compared to S. pneumoniae S protein is 21% using Clustal Omega. Gene co-occurrence in several bacilli genomes (data obtained from genome annotation in NCBI: see Methods). Multiple sequence alignment of possible S protein sequences of several bacilli. Sequence similarities are highlighted in dark blue. (C) AlphaFold model of the S protein of different bacilli bacteria.
