Extended Data Fig. 2: PBP1a and PgdA conservation in Streptococci. | Nature Microbiology

Extended Data Fig. 2: PBP1a and PgdA conservation in Streptococci.

From: Pneumococcal S protein coordinates cell wall modification and repair to resist host antimicrobials

Extended Data Fig. 2: PBP1a and PgdA conservation in Streptococci.

(A) PBP1a and PgdA conservation in Streptococci. Lineage tree based on 16S rRNA sequence of each specie (see methods) was constructed using MEGA. Mycobacterium tuberculosis was used as an outgroup and numbers represent bootstrap. Percentages indicate the percent identity of PBP1a and PgdA for each species compared to S. pneumoniae PBP1a and PgdA respectively. (B) Multiple sequence alignment of Streptococci PBP1a or PgdA sequences. Sequence similarities are highlighted in dark blue.

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