The release of a more genetically stable form of a live, attenuated oral polio vaccine, nOPV2, was heralded as a major advance towards global polio eradication. Virus recombination events can undo all the hard work.
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Thorley, B.R. Double recombinant nOPV2 vaccine. Nat Microbiol (2026). https://doi.org/10.1038/s41564-025-02228-9
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DOI: https://doi.org/10.1038/s41564-025-02228-9