Extended Data Fig. 10: Apical secretion of cytokines from organoid monolayers treated with pfoA− and pfoA+ Clostridium perfringens isolates (n = 2-3 per treatment).

Conditions with the same letters are not significantly different. Data are presented as mean values +/- standard deviation. Statistical comparisons were performed using an ANOVA, followed by adjustment for multiple comparisons using two-tailed Tukey’s HSD method. (A) Apical MIF secretion from organoid monolayers treated with live C. perfringens. (B) Apical IL1RA secretion from organoid monolayers treated with live C. perfringens. (C) Apical IL18 secretion from organoid monolayers treated with live C. perfringens.