Extended Data Fig. 3: Consistency of TRACS SNP distance estimation across simulated short-read and long-read sequencing technologies. | Nature Microbiology

Extended Data Fig. 3: Consistency of TRACS SNP distance estimation across simulated short-read and long-read sequencing technologies.

From: Strain-level transmission inference across multi-kingdom metagenomic data using TRACS

Extended Data Fig. 3: Consistency of TRACS SNP distance estimation across simulated short-read and long-read sequencing technologies.The alternative text for this image may have been generated using AI.

The inferred versus simulated distance of running TRACS on simulated mixtures of pneumococcal strains, where each sample pair is simulated to have a single strain transmitted at the given SNP distance. Here, both Illumina (red) and Nanopore R10.4.1 (blue) sequencing reads have been simulated using the ART and Badread simulators, respectively. Boxplots indicate the distribution of the inferred number of SNPS. The central line represents the median, the edges of the box indicate the interquartile range (IQR), and the whiskers extend to 1.5 times the IQR. This indicates that TRACS can be used with high-accuracy long read sequencing technology.

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