Extended Data Fig. 4: The interaction between CIPS and RBDs.

Snapshots from a representative trajectory for RBD and CIPS interaction in System 1 based on MD simulation. The time points shown below indicate the moments that the series of amino acids appear for the first time. The bottom row indicates the dynamic process of RBD adsorption on the surface of CIPS. The upper row shows the bottom view of the amino acid sites of RBD that bind with CIPS, where van der Waals spheres are the residues contacting CIPS (red, polar residues; green, hydrophobic residues; blue, positively charged residues; purple, negative residues; yellow, cysteines containing disulfide bonds).