Extended Data Fig. 1: Screening of nanomaterials for potential inhibition of SARS-CoV-2 infection. | Nature Nanotechnology

Extended Data Fig. 1: Screening of nanomaterials for potential inhibition of SARS-CoV-2 infection.

From: A nanomaterial targeting the spike protein captures SARS-CoV-2 variants and promotes viral elimination

Extended Data Fig. 1: Screening of nanomaterials for potential inhibition of SARS-CoV-2 infection.

a) TEM images of the examined NMs. Scale bar = 50 nm. b) The effect of NMs on the infection rate (red) and cell viability (black) of ACE2/293 T cells infected with SC2-P. LUC-containing SC2-P pre-incubated with different NMs was used for infecting ACE2/293 T cells. Infection was evaluated on cell lysates as SC2-P dependent luciferase activity after 40 h, while the percentage of metabolically active viable cells was evaluated with the CCK8 assay after exposure to NM for 48 h. Results are presented as mean Âħ SEM of n = 3-5 biological replicates. Statistical significance was calculated by one-way ANOVA with Tukey’s multiple comparisons test.

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