Extended Data Fig. 4: Snapshots of Siglec-5 and −3 in the VcMD simulations. | Nature Nanotechnology

Extended Data Fig. 4: Snapshots of Siglec-5 and −3 in the VcMD simulations.

From: Carbon nanotube recognition by human Siglec-14 provokes inflammation

Extended Data Fig. 4

a and b, Snapshots of Siglec-5 (a) and −3 (b) binding to CNT with the mode 2. All the four interfaces (labelled as (1) to (4)) directed to the CNT surface. However, Siglec-3 does not have side chains with π-electron system which attractively interact with the CNT surface. c and d, Snapshots of Siglec-5 (c) and −3 (d) binding to CNT with the mode 1*, which makes contact with CNT via the interface (2).

Back to article page