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Decoding the cell state from the nanoscale architecture of the cell-surface glycome

Nature Nanotechnology (2026) Cite this article

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Glycan atlassing is a method for the detection of the spatial organization of cell-surface glycosylation patterns at nanoscale. It shows that such patterns reflect the functional state of the cell, providing direct evidence that the cell-surface glycome encodes biological information via its spatial organization.

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Fig. 1: Glycan atlassing traces cancer progression in a cell-based model of EMT.
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References

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This is a summary of: Joseph, D. M. et al. Glycan atlassing enables functional tracing of cell state. Nat. Nanotechnol. https://doi.org/10.1038/s41565-026-02151-y (2026).

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Decoding the cell state from the nanoscale architecture of the cell-surface glycome. Nat. Nanotechnol. (2026). https://doi.org/10.1038/s41565-026-02154-9

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