Fig. 7: PET for quantitative coronary atherosclerosis imaging. | Nature Reviews Cardiology

Fig. 7: PET for quantitative coronary atherosclerosis imaging.

From: Clinical quantitative coronary artery stenosis and coronary atherosclerosis imaging: a Consensus Statement from the Quantitative Cardiovascular Imaging Study Group

Fig. 7: PET for quantitative coronary atherosclerosis imaging.

a, Demonstration of active microcalcification using 18F-NaF PET. Images taken from the PREFFIR trial130 show active microcalcification in culprit, stented plaque in the left anterior descending coronary artery. The CT image (left panel) shows the stent in the left anterior descending coronary artery without a visible abnormality, whereas the PET/CT image (right panel) shows a focal site of increased active mineral deposition (Fig. 2). b, The panel shows the detection of C-X-C chemokine receptor type 4 (CXCR4)-positive inflammatory cells. CT and fused CXCR4-targeted PET/CT of a culprit stented lesion in acute ST-segment elevation myocardial infarction are shown. An elevated CXCR4 signal (top right panel, dashed circle) representing CXCR4+ inflammatory cell infiltrate134 can be observed; the corresponding invasive coronary angiography (ICA) images show the culprit lesion before (bottom left panel, dashed circle) and after (bottom right panel) reperfusion. SUV, standard uptake values.

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