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Atheroimmunology: keeping the immune system in atherosclerosis in check

The immune response is not unlike a game of chess, with white and black pieces playing opposing roles and orchestrating an opening, a middle and an endgame of innate immunity, adaptive immunity and resolution, respectively. After decades of research, the study of atheroimmunology has brought the first therapeutics to the clinic. Can we resynchronize the immune system in atherosclerosis and save the king?

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Fig. 1: Milestones in atheroimmunology research.

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Correspondence to Claudia Monaco.

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Monaco, C., Dib, L. Atheroimmunology: keeping the immune system in atherosclerosis in check. Nat Rev Cardiol 21, 737–738 (2024). https://doi.org/10.1038/s41569-024-01075-1

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