When generative artificial intelligence (AI) draws molecules, it doesn’t just get the science wrong — it risks reshaping how we see chemistry, spreading incorrect representations of our world that mislead learners, distort peer-reviewed reports, and erode trust in scientific work and rigour.
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References
Francl, M. A molecule with a ring to it. Nat. Chem. 7, 6–7 (2015).
Weisberg, M., Needham, P. & Hendry, R. Philosophy of chemistry. In The Stanford Encyclopedia of Philosophy (ed. Zalta, E. N.) (Stanford Univ., 2019).
Matta, C. F. & Gillespie, R. J. Understanding and interpreting molecular electron density distributions. J. Chem. Educ. 79, 1141 (2002).
Mehta, A. ‘Chemistry will no longer be an exclusive club’: how AI is changing Omar Yaghi’s work. Chemistry World (3 February 2025); https://go.nature.com/3VrjUG8.
Kamkar, M. et al. Artificial intelligence (AI) for sustainable resource management and chemical processes. ACS Sustain. Chem. Eng. 12, 2924–2926 (2024).
Regulation (EU) 2024/1689 of the European Parliament and of the Council of 13 June 2024 Laying Down Harmonised Rules on Artificial Intelligence, Document 32024R1689 (European Union, 2024); https://eur-lex.europa.eu/eli/reg/2024/1689/oj/eng.
Why Nature will not allow the use of generative AI in images and video. Nature 618, 214 (2023).
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Moores, A., Zuin Zeidler, V.G. Don’t let generative AI shape how we see chemistry. Nat Rev Chem 9, 649–650 (2025). https://doi.org/10.1038/s41570-025-00757-9
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DOI: https://doi.org/10.1038/s41570-025-00757-9