Metal–organic frameworks are increasingly used in environmental technologies, whereby their biomolecular coronas determine their identity, transport, persistence and ecosystem effects. We argue that further research is needed to embed corona considerations into framework systems design and regulation, and we outline the minimal, actionable steps needed to achieve this.
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Acknowledgements
P.D. and I.L. acknowledge the UKRI Innovate UK Horizon Europe Guarantee Fund (project number 10097888) which supports UoB’s participation in INSIGHT (Grant Agreement No. 101137742) and the UKRI Innovate UK Horizon Europe Guarantee Fund (project number 10097944) which supports UoB’s participation in PINK (Grant Agreement No. 101137809). S.C. acknowledges UKRI NERC Independent Research Fellowship (Grant number - NE/B000187/1)) for supporting this work.
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2025 Nobel Prize in Chemistry: https://www.nobelprize.org/prizes/chemistry/2025/summary/
EU’s Safe and Sustainable by Design Framework: https://publications.jrc.ec.europa.eu/repository/handle/JRC128591
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Dhumal, P., Chakraborty, S. & Lynch, I. Biomolecular coronas govern the environmental fate of metal–organic frameworks. Nat Rev Chem (2026). https://doi.org/10.1038/s41570-025-00789-1
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DOI: https://doi.org/10.1038/s41570-025-00789-1
