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HAEMATOLOGICAL CANCER

When an embarrassment of riches isn’t enough

Data on a new treatment approach utilizing bispecific monoclonal antibodies targetting B-cell maturation antigen (BCMA) were recently published, yielding very encouraging results in the setting of relapsed and/or refractory multiple myeloma (RRMM). How to safely and effectively deliver this treatment to patients and where it fits in the RRMM treatment paradigm are important questions for the future.

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Acknowledgements

S.L. receives support from the Paula and Rodger Riney Foundation and holds the Anne and Bernard Gray Family Chair in Cancer.

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Correspondence to Sagar Lonial.

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K.P. has acted as a consultant for Arcellx, BMS, Caribou Biosciences, Celgene, Cellectis, Janssen, Karyopharm, Legend Biotech, Merck, Nektar, Pfizer, Takeda. S.L. has acted as a consultant for ABBVIE, Amgen, BMS, Celgene, GSK, Janssen, Novartis, Takeda, is a member of the board of directors and holds stock in TG therapeutics.

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Patel, K., Lonial, S. When an embarrassment of riches isn’t enough. Nat Rev Clin Oncol 19, 617–618 (2022). https://doi.org/10.1038/s41571-022-00670-w

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