Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Research Highlight
  • Published:

THYROID DISEASE

Long-term treatment outcomes for Graves disease

Nature Reviews Endocrinology volume 15, page 628 (2019)Cite this article

Subjects

Three therapies exist for Graves disease (also known as Graves hyperthyroidism): antithyroid drug therapy (ATD), radioactive iodine (I131 therapy) to damage the thyroid or surgery to remove all or part of the thyroid. The efficacy of each of these treatments is well known; however, little is known about the long-term outcomes of each treatment modality. A new study in Thyroid presents long-term (6–10 years) outcome data for the different treatments of Graves disease.

The proportion of patients that were available at follow-up was 60% (1,186 individuals). The first-line treatment of choice was ATD, followed by I131 therapy and then surgery. However, the remission rate after the first-line treatment was 45.3% (351/774) with ATD, 81.5% (324/264) with I131 therapy and 96.3% (52/54) with surgery.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on SpringerLink
  • Instant access to the full article PDF.

USD 39.95

Prices may be subject to local taxes which are calculated during checkout

References

Original article

Download references

Author information

Authors and Affiliations

  1. Nature Reviews Endocrinology http://www.nature.com/nrendo/

    Shimona Starling

Authors
  1. Shimona Starling
    View author publications

    Search author on:PubMed Google Scholar

Corresponding author

Correspondence to Shimona Starling.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Starling, S. Long-term treatment outcomes for Graves disease. Nat Rev Endocrinol 15, 628 (2019). https://doi.org/10.1038/s41574-019-0268-5

Download citation

  • Published:

  • Version of record:

  • Issue date:

  • DOI: https://doi.org/10.1038/s41574-019-0268-5

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing