Table 2 Potential extra-skeletal benefits of vitamin D supplementation in individuals with vitamin D deficiency at baseline
From: The health effects of vitamin D supplementation: evidence from human studies
Authors and ref. | Outcome | Overall results | Results in vitamin D-deficient participants |
|---|---|---|---|
Sluyter et al.44 | Brachial blood pressure | NS | NS |
Central blood pressure: systolic | NS | −7.5 mm (P = 0.03) | |
Central blood pressure: diastolic | NS | NS | |
Six other parameters | NS | P = 0.03–0.003 | |
Sluyter et al.86 | All participants: lung function (FEV1) | +16 ml (NS) | +39 ml (NS) |
Substudy (n = 442, follow-up 1.1 years): participants with asthma or COPD | +40 ml (NS) | +109 ml (P = 0.08) | |
Substudy (n = 442, follow-up 1.1 years): participants who had ever-smoked | +57 ml (P = 0.03) | +112 ml (P = 0.04) | |
Substudy (n = 442, follow-up 1.1 years): participants who had ever-smoked with asthma or COPD | +160 ml (P = 0.004) | NA | |
Wu et al.a (ref.124) | Pain impact score | NS | NS |
Prescription of opioids | NS | NS | |
Prescription of NSAIDs | NS | RR 0.87 (P = 0.01) | |
Pittas et al.b (ref.17) | Progression of prediabetes into T2DM: post hoc analysis (n = 103) | NS | HR 0.38 (95% CI 0.18–0.80) |
