This Genome Watch highlights different tools and strategies used to enhance the quality of metagenome-assembled genomes (MAGs) generated in microbiome studies.
Enjoying our latest content?
Log in or create an account to continue
- Access the most recent journalism from Nature's award-winning team
- Explore the latest features & opinion covering groundbreaking research
or
References
Bowers, R. M. et al. Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea. Nat. Biotechnol. 35, 725–731 (2017).
Parks, D. H. et al. CheckM: assessing the quality of microbial genomes recovered from isolates, single cells, and metagenomes. Genome Res. 25, 1043–1055 (2015).
Chklovski, A. et al. CheckM2: a rapid, scalable and accurate tool for assessing microbial genome quality using machine learning. Nat. Methods 20, 1203–1212 (2023).
Mattock, J. & Watson, M. A comparison of single-coverage and multi-coverage metagenomic binning reveals extensive hidden contamination. Nat. Methods 20, 1170–1173 (2023).
Bornemann, T. L. V. et al. uBin: a manual refining tool for genomes from metagenomes. Environ. Microbiol. 25, 1077–1083 (2023).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Malmstrom, R.R. Quality MAGnified. Nat Rev Microbiol 21, 771 (2023). https://doi.org/10.1038/s41579-023-00981-4
Published:
Version of record:
Issue date:
DOI: https://doi.org/10.1038/s41579-023-00981-4
This article is cited by
-
Benchmarking metagenomic binning tools on real datasets across sequencing platforms and binning modes
Nature Communications (2025)
