Table 1 Challenges in managing patients with kidney disease during the COVID-19 pandemic

From: Impact of the COVID-19 pandemic on the kidney community: lessons learned and future directions

Cohort type

Challenges

Solutions

Actions required

AKI

Increased demand for bedside dialysis and CRRT

Shortage of dialysis solutions and workforce

Organization of multidisciplinary crisis team to include nephrologists, nurses and hospital administrators

Taking inventory of all aspects of RRT

Tracking daily need for RRT

Modification of HD and CRRT

protocols to meet increased demand

Utility of acute PD

Redeployment of faculty, trainees and nurses to meet needs

Develop a framework for addressing system capacity, challenges in communication and allocating resources founded on ethical principles

Educate patients about AKI and risks

CKD

Interruption of new consultations and follow-up care

Laboratory monitoring of CKD

Limited pre-dialysis access care due to the pandemic

Lack of data on therapeutics and vaccine response in the CKD population

Adoption of telemedicine for all except urgent cases requiring in-person evaluation

Restrict laboratory tests to those with rapid turnaround for clinical care and use non-hospital-based labs for blood draw

Home urine dipstick monitoring

Include vascular access surgeries and PD catheter placement among essential procedures

Evaluate disparities in digital literacy and establish a protocol to include telemedicine navigators to facilitate telemedicine

Advocacy for inclusion of CKD cohorts in clinical trials of therapeutics and vaccines

Patients with ESKD on maintenance dialysis

Safe continuation of thrice weekly in-centre dialysis

Training for home dialysis modalities and longitudinal care for home dialysis patients

Delay in dialysis access placement

Delays in transplant evaluation and placement on waiting list

Lack of data on therapeutics and vaccine response in the ESKD population

Protocol for symptom screening for infection and universal masking

Cohorting infected patients in designated COVID units

Wider adoption of home dialysis modalities

Conversion from in-person to televisit for in-centre and home dialysis patients

Inclusion of dialysis access as an essential procedure

Reduction of dialysis sessions to twice a week

Conversion to home dialysis

Universal viral testing for symptomatic in-centre dialysis patients

Stock-piling of emergency medical equipment and dialysis supplies

Adoption of assisted peritoneal dialysis and home hemodialysis

Development of algorithms to accelerate evaluation and placement of medically stable individuals on waiting list

Inclusion of patients with ESKD in clinical trials of therapeutics and vaccines

Kidney transplant recipients

Strategies to reduce risk of infection

Continuation of evaluation for transplant candidacy

Continuation of transplant surgeries

Evaluating vaccine efficacy

Adoption of telemedicine and remote monitoring

Suspension of live donation and decrease in DDKT

Vaccine prioritization, booster doses, vaccination of household contacts

Leveraging health care technology to aid remote monitoring of vital signs and glucose

Algorithm for individualized approach to continuing transplant surgery

Strategies to enhance vaccine efficacy

Immune-mediated kidney disease

Strategies to reduce risk of infection

Identifying immunosuppressive classes associated with increased risk of infection

Evaluating vaccine efficacy

Adoption of telemedicine and remote monitoring

Decrease in frequency of laboratory monitoring

Delaying use of biologics in stable patients

Vaccine prioritization, booster doses, vaccination of household contacts

Leveraging health care technology to aid remote monitoring of disease activity and adoption of urine dipstick monitoring

Comparing utility of non-invasive disease biomarkers and kidney biopsy for glomerular diseases

Algorithms to personalize maintenance immunosuppressive therapy for relapsing diseases

Strategies to enhance vaccine efficacy

Children living with kidney disease

Interruption of follow-up care for CKD

Continuation of transplant surgeries

Lack of data on therapeutics and vaccine response in the CKD population

Psychological impact of isolation and shielding

Caregiver burden

Adoption of telemedicine and remote monitoring

Suspension of live donation

Wider adoption of home dialysis

Strategies to address caregiver burden

Inclusion of children in clinical trials and prioritization of high-risk groups for vaccines

Research into kidney health and cardiovascular consequences of the pandemic

Address paediatric health equity through research and public policy

Ensure resources to maintain critical services for children on dialysis

Utilize patient-reported outcomes along with relevant health measures

  1. AKI, acute kidney injury; CKD, chronic kidney disease; CRRT, continuous renal replacement therapy; DDKT, deceased donor kidney transplantation; ESKD, end-stage kidney disease; HD, haemodialysis; PD, peritoneal dialysis; RRT, renal replacement therapy.