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The promise of digital twins as a tool for personalized approaches in nephrology

Nature Reviews Nephrology volume 22, pages 3–4 (2026)Cite this article

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Digital twins are a key computational technology for the implementation of personalized approaches to medical care. They are based on computational models that have been calibrated to an individual patient and can be used to identify personalized treatment approaches. Nephrology offers several promising potential applications for this technology.

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Fig. 1: An example of potential use of medical digital twin technology in critical care nephrology.

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Authors and Affiliations

  1. Department of Medicine, University of Florida, Gainesville, FL, USA

    Reinhard Laubenbacher & Parta Hatamizadeh

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  1. Reinhard Laubenbacher
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  2. Parta Hatamizadeh
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Correspondence to Reinhard Laubenbacher.

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Competing interests

P.H. is the inventor of a pending patent through University of Florida entitled “Renal replacement therapy machine”. The authors declare no other competing interests.

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Laubenbacher, R., Hatamizadeh, P. The promise of digital twins as a tool for personalized approaches in nephrology. Nat Rev Nephrol 22, 3–4 (2026). https://doi.org/10.1038/s41581-025-01021-5

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  • DOI: https://doi.org/10.1038/s41581-025-01021-5

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