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A frequency location to remember

Nature Reviews Neuroscience volume 23, pages 644–645 (2022)Cite this article

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Ageing-related memory deficits impair abilities that are essential for daily life. The large-scale population dynamics that underpin working memory (WM) and long-term memory (LTM) can be targeted using innovative neuromodulation technologies, but whether these can improve memory is unknown. Here, Grover et al. demonstrate in older adults that low-frequency and high-frequency neuromodulation in specific brain areas selectively enhances WM and LTM, respectively.

The authors found that neuromodulation selectively improved LTM in the DLPFC-gamma group, whereas it selectively improved WM in the IPL-theta group, compared to the sham-control group. These improvements were apparent by the second day of neuromodulation in the DLPFC-gamma group and by the third day in the IPL-theta group. In both cases, the memory performance improvements lasted at least 1 month after the neuromodulation had ceased.

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  1. Nature Reviews Neuroscience http://www.nature.com/nrn/

    Jake Rogers

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  1. Jake Rogers
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Correspondence to Jake Rogers.

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Rogers, J. A frequency location to remember. Nat Rev Neurosci 23, 644–645 (2022). https://doi.org/10.1038/s41583-022-00635-z

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