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A firm grip on hand OA: 20 years of progress and prospects

Nature Reviews Rheumatology volume 21, pages 646–647 (2025)Cite this article

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In the past two decades the field of hand osteoarthritis (OA) has moved from resignation to action. Despite progress, such as the recognition of the phenotypic heterogeneity of hand OA (including inflammation- and/or metabolic syndrome-associated hand OA) and the standardization of imaging and treatment outcomes, challenges remain in achieving truly disease-modifying therapies.

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Authors and Affiliations

  1. Sorbonne University, Inserm CRSA, Paris, France

    Francis Berenbaum

  2. Department of Rheumatology, AP-HP Saint-Antoine hospital, Paris, France

    Francis Berenbaum & Emmanuel Maheu

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  1. Francis Berenbaum
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  2. Emmanuel Maheu
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Correspondence to Francis Berenbaum.

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The authors declare no competing interests.

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Berenbaum, F., Maheu, E. A firm grip on hand OA: 20 years of progress and prospects. Nat Rev Rheumatol 21, 646–647 (2025). https://doi.org/10.1038/s41584-025-01304-y

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