Correction to: Nature Reviews Rheumatology https://doi.org/10.1038/s41584-025-01287-w, published online 11 August 2025.

In the version of the article initially published, in Fig. 1, the box reading “↑ OPG” should have read “↓ OPG”. In the Fig. 1 caption, the text “...results in increased expression of receptor activator of NF-ᴋB ligand (RANKL) and osteoprotegerin (OPG) in osteoclasts, and sustained RANKL–OPG signalling supports osteoclast activation, resulting in bone resorption” should have read “...results in increased expression of receptor activator of NF-ᴋB ligand (RANKL) and downregulation of osteoprotegerin (OPG) in osteoclasts, leading to osteoclast activation, and resultant bone resorption”. These corrections have now been made to the HTML and PDF versions of the article.