Extended Data Fig. 5: ENOS binding correlates with future enhancer activity.
From: Pluripotency factors functionally premark cell-type-restricted enhancers in ES cells
a–d, Comparison of the approximately 10% ‘most’ marked (high) and ‘least’ marked (low) enhancers selected on the basis of ENOS binding, and the level of H3K4me1 and H3K27Ac on these enhancers in mature tissues for spleen (a), lung (b), cortex (c) and bone marrow (d). In the box plots, line shows median and box shows 25th and 75th percentiles. Red dots indicate each value of H3K4me1 or H3K27Ac. P values calculated using Welch’s two-sided t-test. Data from published sources are listed in Supplementary Table 1.
