Extended Data Fig. 3: Structures, yields, IC50 values and ASMS comparison plots for the MK2 Library. | Nature

Extended Data Fig. 3: Structures, yields, IC50 values and ASMS comparison plots for the MK2 Library.

From: Nanoscale synthesis and affinity ranking

Extended Data Fig. 3

a, A library of 18 unique MK2 inhibitors (5, 6, B1–B16) was produced by coupling 4 to diverse boronates under eight reaction conditions (see Fig. 2b). b–e, As in Extended Data Fig. 2, but for MK2 and IC50 values instead of ERK2 and Ki values.

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