Extended Data Fig. 8: ROC for infection detection using different testing protocols.
From: Reconstruction of antibody dynamics and infection histories to evaluate dengue risk
The ROC for different assay approaches and time between blood draws calculated from 100,000 simulated titre responses. a, Single serotype assay—when haemagglutination inhibition tests are conducted for only a single serotype at two time points. b, Haemagglutination inhibition tests conducted against all four serotypes. Infections are considered to occur when the ratio of any of the four titres at time point 2 versus time point 1 is greater than the threshold value. c, Haemagglutination inhibition tests conducted against all four serotypes. Infections are considered to occur when the ratio of the mean of the four titres at time point 2 versus the mean at time point 1 is greater than the threshold value.
