Extended Data Fig. 8: Gene expression curves in E12.5 cells.
From: Single-cell analysis of early progenitor cells that build coronary arteries
a, Expression of genes from the indicated categories along the SV–CV plexus–arterial differentiation continuum. The x-axis has individual cells organized as shown in Fig. 3a, and gene expression is plotted as LOESS curves. Raw data points are shown as dots. b, GSEA; cell cycle pathways shown in bold. c, Pre-artery cells (Cx40+Cxcr4+Apj−) segregate to the non-cycling quadrant of rPCA plots. Arrows indicate cell cycle progression. d, Quantification of EdU labelling in pre-artery cells. Data shown as mean ± s.d. n = 6 hearts. ***P ≤ 0.001. Unpaired two-tailed t-test was used to calculate P value.
